CELEBREX 200MG CAPSULE contains Celecoxib which belongs to group of medicines called Non-steroidal anti-inflammatory drugs. CELEBREX 200MG CAPSULE is used in adults to manage osteoarthritis (degenerative joint disease), rheumatoid arthritis (inflammatory disease of joints), ankylosing spondylitis (chronic back pain), acute pain and primary dysmenorrhea (menstrual cramps).
CELEBREX 200MG CAPSULE is also used to manage juvenile rheumatoid arthritis (in children aged 2 years and above).
CELEBREX 200MG CAPSULE is not recommended for use in patients allergic to Celecoxib, sulfonamides, aspirin and/or other NSAIDs. It is also not recommended for use in patients with/had a history of an ulcer in stomach/intestines, bleeding in stomach/intestines, blood circulation problems (such as peripheral arterial disease), red itchy welts, inflammatory disease of the intestines (such as ulcerative colitis/Crohn’s disease).
The medicine is also not indicted for use in patients suffering from lung problems (such as asthma), heart diseases (such as heart failure, recent heart attack, heart block), severe liver disease (such as advanced hepatic insufficiency) and/or kidney disease (such as advanced renal insufficiency).
Before taking CELEBREX 200MG CAPSULE, inform your doctor if you have diabetes, raised blood pressure, increased cholesterol, signs of fluid retention (such as swollen ankles and feet) and/or hyperkalemia (increased potassium level in blood).
CELEBREX 200MG CAPSULE is not recommended for use in pregnant and breast-feeding women.
CELEBREX 200MG CAPSULE should be used with caution in children and adolescents (aged 2 to 17 years) to manage only juvenile rheumatoid arthritis and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.
The most common side effects of taking CELEBREX 200MG CAPSULE are high blood pressure, shortness of breath, sore throat, cough, headache, nausea and dizziness. Consult your doctor if any of these symptoms worsen.
How should I take CELEBREX 200MG CAPSULE?The usual dose of CELEBREX 200MG CAPSULE is 200 mg twice a day, divided into 2 x 500 mg (2 x 200mg) tablet parts.
CELEBREX 200MG CAPSULE should be taken at the same time each day as prescribed by your doctor. Do not stop taking CELEBREX 200MG CAPSULE without the doctor’s approval.
The duration of treatment is up to 2 weeks, but it is important to finish the medicine as scheduled and to stop taking it at the recommended time.
<>CELEBREX 200MG CAPSULE should be swallowed whole; break it down 1. time each day.The dose of CELEBREX 200MG CAPSULE varies depending on the patient’s condition and how he reacts to the treatment. However, if the patient feels that the treatment is not working, the dose can be increased.
Consult your doctor if any of these symptoms go away.
The duration of treatment is up to 2 weeks, but some side effects (such as loss of appetite, vomiting, nausea) may get better after. If you notice other side effects not mentioned in this medication guide, talk to your doctor or pharmacist.
Can I get CELEBREX 200MG CAPSULE for more than 1 year?You can get CELEBREX 200MG CAPSULE online through Pharmacycom.com. But, if you are a US citizen, you will need to go through a simple process with a valid prescription.
No, CELEBREX 200MG CAPSULE cannot be given for longer than 1 year. Do not take more than one dose of CELEBREX 200MG CAPSULE per day without consulting a doctor.
Can I take CELEBREX 200MG CAPSULE with food?CELEBREX 200MG CAPSULE can be taken with or without food.
Celebrex is a prescription medication used to treat pain and inflammation caused by arthritis, rheumatoid arthritis (RA), or other conditions related to the body’s production of a substance called a prostaglandin.
Celebrex is an NSAID medication that works by blocking an enzyme called cyclooxygenase (COX), which is responsible for the production of prostaglandins that cause pain and inflammation. COX-1, 2, and 3 are the two most widely known forms of COX, while the others are mainly found in the liver and kidneys.
Celebrex is a popular drug used to treat pain and inflammation, but it is not a first-line treatment.
Celebrex has been available for several years, but it has been discontinued because of concerns it might be linked to an increased risk of heart attack or stroke.
Celebrex is a prescription medication used to treat pain and inflammation caused by an abnormal production of a prostaglandin (PG) that causes pain and inflammation. It also helps to decrease symptoms of arthritis, such as stiffness and joint pain, when they occur.
Celebrex is not intended for long-term use; however, it can be used to treat acute pain, such as those that occur after a physical procedure or surgery, and those that are chronic or recurrent.
Celebrex is available only with a prescription from a healthcare provider, so it is important to understand that it is not a first-line treatment for pain.
Celebrex is usually taken orally. It is typically taken once or twice a day for pain relief. It is important to follow your healthcare provider’s instructions when taking Celebrex.
Celebrex is usually taken once or twice a day for pain relief.
Do not take Celebrex with a meal that contains a high-fat meal, such as a cheeseburger and french fries, or with a dairy product such as milk or yogurt.
Celebrex may be taken with or without food, but it is essential to take it with food or a large meal to minimize stomach upset.
Celebrex can be taken with or without food, but it is essential to be aware that it can be taken with or without food. Therefore, it is advisable to avoid consuming too much Celebrex in an amount that is too close to your stomach.
You should also avoid taking Celebrex with other medications that are used to treat inflammation or pain, such as aspirin or NSAIDs like ibuprofen.
It is important to note that Celebrex may not be suitable for people with certain medical conditions, such as kidney or liver disease.
Celebrex may increase the risk of heart attack or stroke, especially if you take the medication for a long time or if you have heart rhythm problems.
It is important to talk to your healthcare provider about any concerns you may have about Celebrex, including any possible risks that may occur. They can help determine if the benefits of Celebrex are worth the risks associated with the medication.
Celecoxib (Celebrex, brand names such as Celebrex, Celebrex XR, and Celebrex XR, generically) is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation (inflammation) associated with conditions such as arthritis, muscle and joint injuries. The FDA has approved Celecoxib as an anti-inflammatory and analgesic, but it is contraindicated for the treatment of osteoarthritis, ankylosing spondylitis, and nonsteroidal anti-inflammatory drug (NSAID)-related conditions. The potential for its use is limited by the fact that the NSAID’s main active ingredient is COX-1 enzyme inhibitors, which means they can lead to gastrointestinal side effects, including gastrointestinal bleeding, ulceration, and perforation of the stomach or intestines [
]. This is a serious problem for patients who take NSAIDs in large doses and for whom it is contraindicated. This is a further concern for physicians due to the risk of gastrointestinal toxicity. In a previous study, we found that NSAIDs can cause serious gastrointestinal bleeding, and patients with gastrointestinal bleeding were prescribed multiple NSAIDs, including Celebrex, for a long time [
As a result of this, it was decided to evaluate whether the use of selective COX-2 inhibitors, such as celecoxib, could induce gastrointestinal damage.
We performed a clinical study that included 753 patients with osteoarthritis who were randomly assigned to receive celecoxib or placebo for 7 months. Patients were randomized to receive either celecoxib or placebo, and the study was conducted at an average age of 65 years.
Patients with osteoarthritis were enrolled in a randomized clinical trial and randomized to receive celecoxib (200 mg) or placebo (1000 mg) at the beginning of the study (pre-treatment) and at the end of the study (post-treatment). Patients with rheumatoid arthritis were excluded from the study. Written informed consent was obtained from all patients.
Of the 753 patients enrolled, we found that the mean age of the patients was 65.0 ± 3.0 years, and the mean duration of NSAID use was 19.1 ± 5.1 years. The most common adverse events were gastrointestinal bleeding (9.7%), gastrointestinal perforation (6.4%), and perforation (5.3%) [
Compared to the placebo group, celecoxib (n = 594) led to a higher incidence of gastrointestinal bleeding (7.3%), gastrointestinal perforation (6.4%), and perforation (5.3%) (
). Celecoxib was associated with an increased risk of gastrointestinal bleeding (OR: 0.8; 95% CI: 0.4, 1.4; p = 0.025) [
The most frequent adverse events were gastrointestinal perforation (22.9%), gastrointestinal bleeding (9.7%), and gastrointestinal perforation (6.4%).
The overall prevalence of adverse events in this study was low (1.7%). The most common adverse events associated with celecoxib and placebo were gastrointestinal perforation (22.8%), gastrointestinal bleeding (11.2%), and perforation (8.1%).
In addition to gastrointestinal bleeding, we found that patients with osteoarthritis were also more likely to have a history of gastrointestinal perforation (9.0%) than those with rheumatoid arthritis (10.0%).
Compared to the placebo group, celecoxib (n = 594) led to a higher incidence of gastrointestinal bleeding (2.8%) (
Compared to the celecoxib group, the incidence of gastrointestinal perforation (2.4%) was the highest in patients with rheumatoid arthritis (7.3%), while the incidence of perforation was the lowest in patients with osteoarthritis (5.4%).
Overall, the incidence of gastrointestinal perforation was higher in the celecoxib group than the celecoxib and placebo groups. In addition, gastrointestinal perforation was associated with higher rates of blood clots, and higher rates of bleeding compared to placebo.
Celebrex 200mg capsule contains the active ingredient Celecoxib. It belongs to the family known as non-steroidal anti-inflammatory drugs (NSAID), and specifically a sub-group known as cyclooxygenase-2 (COX-2) inhibitors. It is used in adults for the relief of signs and symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. In conditions like rheumatoid arthritis and osteoarthritis, excess production of prostaglandins by your body can lead to pain and inflammation. This medicine works by decreasing the production of prostaglandins, effectively reducing pain and inflammation.
Do not take Celebrex 200mg capsule if you are allergic to Celecoxib or any of its ingredients. Inform your doctor if you had reactions to sulfonamide medicines, suffer from ulcers or bleeding in the stomach or intestines, or experienced adverse reactions to NSAID medications like aspirin. Before starting the treatment, inform your doctor because it is recommended to not take this medicine if you are pregnant or are breastfeeding. Do not take this medicine if you have severe liver or kidney disease, have inflammatory intestinal conditions, or have heart-related issues such as heart failure, heart disease, or circulation problems. Additionally, if you have had surgeries on leg arteries or have a history of blood circulation problems, this medicine usage should be avoided. This contains lactose. If you are sugar intolerant, consult your doctor before using this product. This medicine is for adults only, it is not for use in children.
Inform your doctor about if you have a history of stomach or intestinal ulcers or bleeding (avoid if currently present), are on acetylsalicylic acid or antiplatelet therapies, use blood clotting or corticosteroid medications, or simultaneously use other non-acetylsalicylic NSAIDs like ibuprofen. Report your doctor if you have conditions such as smoking, diabetes, high blood pressure, high cholesterol, compromised heart, liver, or kidney function, fluid retention, dehydration, past severe allergic reactions to medications, ongoing infections, or are over 65 years old. Monitoring may be necessary. Notably, Celebrex 200mg capsule could mask fever or infection signs. Remember, alcohol combined with NSAIDs may increase gastrointestinal risks.
Celecoxib 200mgCelebrex 200mg capsule belongs to a class of drugs known as COX-2 inhibitors. It works by decreasing the production of the pro-inflammatory substances, prostaglandins, which are responsible for pain and inflammation. By reducing the production of prostaglandins, Celebrex 200mg capsule helps reduce inflammation and pain. It relieves pain and inflammation without causing any gastrointestinal side effects. It also reduces the risk of serious gastrointestinal risks associated with Celebrex 200mg capsule. However, because it is used for a purpose, it should not be used in conditions like heart disease, ulcers, bleeding or gastrointestinal bleeding. Additionally, it is not recommended for use in managing osteoarthritis or rheumatoid arthritis. Discuss your symptoms and medical history with a doctor before starting Celebrex 200mg capsule.
Celecoxib 200mg capsule can cause side effects, although not everyone experiences them. Common side effects include:
It is important to note that not everyone will experience these side effects. If you experience side effects, talk to your doctor before using Celebrex 200mg capsule.
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